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Description
What happens when people stop GLP 1 weight loss drugs? A recent paper in eClinicalMedicine analysed weight regain after stopping GLP 1 receptor agonists using a systematic review and nonlinear meta regression of 48 studies. Because GLP 1 Agonists: Using Semaglutide, Tirzepatide, and Orforglipron for Weight Loss and Obesity Semaglutide vs. Tirzepatide: What's the Difference? Semaglutide and tirzepatide are powerful, FDA approved tools for managing weight and blood sugar but they work a little differently, and understanding those differences can Effect of combination treatment with glucagon like peptide 1 receptor agonists and sodium glucose cotransporter 2 inhibitors on incidence of cardiovascular and serious renal events: population based cohort study The BMJ
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.1 ★★★★★
Based on 462 reviews
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Product Reviews
★★★★★ 5
Really nice shoes
Size: 9, Color: Black Polished Full Grain
My husband enjoys wearing these shoes. Very classy looking. They fit well. They arrived quickly. He liked them so much he ordered another pair in a different color which have worked out just as well.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 3, 2026
★★★★★ 3
Way too narrow
Size: 9.5 Wide, Color: Burgundy Polished Full Grain
I ordered a wide in this shoe, but it was still way too narrow. I had to return them. Otherwise, it looked like a nice quality shoe.
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Reviewed in the United States on February 12, 2026
★★★★★ 5
I usually wear 11.5's, but I buy 1/2 size smaller to accommodate for stretch. Leather relaxes.
Size: 11, Color: Burgundy Polished Full Grain
5 STARS: These shoes are awesome. I keep coming back for more. I have major foot problems, have tried all kinds of shoes, orthotics, and inserts... but believe it or not, these shoes work better than any of that stuff. I wear them daily. I buy lots of them, for home, for church, and I'm getting my first pair of J&M boots today, for winters in Indiana... Brrrr
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Reviewed in the United States on December 18, 2025
★★★★★ 5
Great price great shoe
Size: 12, Color: Burgundy Polished Full Grain
Excellent shoe. Tried the Sebago penny loafer and the sizing was ridiculous. These J and M are sized perfectly. I’ve had them before and they wear like iron. Very comfortable right out of the box.
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Reviewed in the United States on May 23, 2026
★★★★★ 5
One of the best shoes
Size: 9.5, Color: Black Polished Full Grain
Outstanding. Fashionable, most comfortable and good construction. No sines of use after quite some time. Highly recommended.
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Reviewed in the United States on March 21, 2026
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